ea0056gp194 | Pituitary Basic | ECE2018
Ku Cheol Ryong
, Kang Chan Woo
, Kim Daham
, Hong Jae Won
, Kim Sun Ho
, Lee Eun Jig
Olfactory marker protein (OMP) is a marker of olfactory receptor-mediated chemoreception, even outside the olfactory system. Here, we report that OMP expression in the pituitary gland plays a role in basal and thyrotropin-releasing hormone (TRH)-induced prolactin (PRL) production and secretion. We found that OMP was expressed in human and rodent pituitary glands, especially in PRL-secreting lactotrophs. OMP knockdown in GH4 rat pituitary cells increased PRL production and secr...